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🚨 New from our lab in #ScienceAdvances! RAD21L cohesin acts as both a 3D genome architect and a transcriptional gatekeeper in the male germline. Its loss disrupts both structure and function—highlighting the tight link between genome folding and gene regulation www.science.org/doi/10.1126/...
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Deletion of the meiotic subunit RAD21L alters 3D chromatin structure and transcription in the mammalian male germ line.
www.science.org
Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline
Aurora Ruiz-Herrera