Study led by Dr. Siragusa (Goethe Uni Frankfurt) reveals thousands of previously unannotated endothelial microproteins and their regulation under inflammatory conditions. The functional relevance of microproteins was demonstrated by large scale CRISPR/Cas9 screen. academic.oup.com/cardiovascre...
AbstractAims. Microproteins (miPs) translated from small open reading frames (smORFs) are crucial regulators of cell function. However, the expression and