Beautiful work from @landau.bsky.social! I wonder if with some tweaks if it can be combined with single cell lentiviral barcoding.
Single-cell mapping of regulatory DNA-protein interactions: Cell www.cell.com/cell/fulltex...
D&D-seq, a single-cell immune-tethering strategy, captures weak and transient DNA-protein
interactions to enable integrated, genome-wide analysis of transcription factor binding
across chromatin state...