Organic Chemist, Group Leader E-Chem Team UniGraz | Postdoc at BaranLab | PhD in Noël Group
2022 #CASFutureLeader, 2021 #RealTimeChem Ambassador.
ORCiD: https://orcid.org/0000-0002-2749-8393
Gabriele Laudadio
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This work opens new possibilities in the field of transition metal electrochemistry. Exciting times ahead. (7/7)
In the mechanistic study, we demonstrated that W not only promotes the DODH reaction but also mediates the pinacol coupling in the electrochemical step.
One metal, multiple purposes! (5/n)
Thanks @pubs.acs.org OPRD for highlighting our work on the autonomous electrochemical platform!
doi.org/10.1021/acs....
Robust and scalable reaction, works with aldehydes, ketones, diols... with prolonged electrolysis the double bond can be even reduced! (4/n)
... But this project still had a lot to offer. Along the way, we discovered that under these conditions, cinnamaldehydes react in a Giese-like addition, leading to aromatization after the thermal step. A simple and effective way to synthesize p-terphenyls. (6/n)
In the literature, precedents showed that chemical and electrochemical approaches could activate W to engage formal carbonyl metathesis. However, when we tried to replicate those results, something was not adding up... Turns out the reaction happened in the liner of the GC! (2/n)
Tungsten Electrochemistry in Organic Synthesis!
In our latest @chemrxiv.org, we present an exciting collaboration with Merck US. An 18-month project carried out by (now Dr.) Nikola Petrovic
Buckle up, story time! (1/n)
chemrxiv.org/doi/full/10....
We figured out that both the electrochemical and the thermal steps were essential to accomplish the reaction, which worked via echem pinacol coupling and thermal deoxydehydration. We streamlined the two steps in flow #gowiththeflow (3/n)
Glad to see our paper published in @greenchemistry.rsc.org
pubs.rsc.org/en/content/a...
Gabriele Laudadio
Gabriele Laudadio
Gabriele Laudadio
Gabriele Laudadio
Self-driving labs are transforming chemistry; but high cost & complexity limit access to a few well-funded labs.
We wanted to change that.
Our new paper in #NatureSynthesis introduces RoboChem-Flex 🧪🤖
🔗https://nature.com/articles/s44160-026-01053-0
#selfdrivinglab #flowchemistry #optimization
Gabriele Laudadio
Gabriele Laudadio
Enabling technologies are perceived as inherently sustainable, due to the replacement of stoichiometric oxidants and reductants with traceless redox mediators such as photons or electrons. However, th...
Electrochemistry to the next sustainable level: In our first work of the year, we present a general water/propylene carbonate mixture to carry out anodic reactions.
Check it out!
t.co/vKTiLTF0ga
