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This is a nice summary of recent studies on dendritic excitability in vivo.
I concur with Andrew's skepticism.
I started a company! Luminos. We made a complete neuro-electronic interface: stimulate and record from any set of neurons in any pattern of space and time, over a 6 mm field of view. Also useful for optical pooled screens and structured illumination live-tissue imaging. luminosmicro.com
Beautiful work, well described.
21d
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1/10 When the going gets tough, the dendrites get going. Here is a summary on our new paper just published in @science.org on flexible learning in frontal motor cortex. With @mattlark.bsky.social 🔬. #neuroskyence #neuroscience 🔗 doi.org/10.1126/scie...
1mo
Flexible learning relies on integrating sensory and contextual information to adjust behavioral output in different environments. The anterolateral motor cortex (ALM) is a frontal area critical for ac...
doi.org
Tuft dendrites in frontal motor cortex enable flexible learning
Eduardo Maristany de las Casas
Super cool, can't wait to see what folks do with this next! Lots of good detail in the 🧵 www.addgene.org/247065/
In this new blog post, I review some several recent studies on dendritic voltage and calcium imaging in hippocampus: gcamp6f.com/2026/05/19/d... Great work by @bhlee1117.bsky.social, Xiang Wu, @adamezracohen.bsky.social, Attila Losonczy, Balazs Rosza, Kevin Gonzalez, and others!
I've been getting questions about this paper all week: www.cell.com/cell/abstrac... They make EXTRAORDINARY claims - fortunately, these are trivial to verify/falsify. Unfortunately, there's other concerns.
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gcamp6f.com
Dendrites are the tree-like arborizations of neurons through which they receive input from other neurons. This compartmentalized anatomy has given rise to the idea that individual dendrites process…
Dendritic imaging of pyramidal neurons in mouse hippocampus
The EMF-inducible gene switch (Ei) platform provides precise spatiotemporal control of gene expression through Cyb5b-mediated calcium oscillations. This system enables Ei-OSK-driven in vivo rejuvenati...
www.cell.com
Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression
Mike Lacy
Peter Rupprecht
Andrew G. York
Meet MagLuc: a magnetically-controlled luminescent protein. This is a foundational tool for remote control of biological processes, also known as "magnetogenetics". Can you tell when the magnetic field turns on and off? From @mariaingaramo.bsky.social and the team at @nonfictionlabs.bsky.social
1mo
Video
Andrew G. York