A team led by Michela Locci, PhD has detailed how the lipid nanoparticles that encapsulate mRNAs in vaccines—and the mRNA molecules themselves—play roles in the potency of the immune response, findings that should be useful for designing future vaccines. https://bit.ly/3MSLbkq
This study dissects the individual contributions of the different components of mRNA
vaccines to immune responses. Nucleoside-modified mRNA promotes the production of
type I interferons that act on de...
