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by @danabra.mov
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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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tinyurl.com/reuxynmc Very excited to see this work I was a small part of published! We analysed two large scale colocalisation datasets: OpenTargets data and an analysis of immune-mediated disease GWAS/immune cell eQTLs seeking to understand the "colocalisation gap". Some highlights:
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Author summary Most of the genetic variants associated with complex traits are located outside genes, limiting functional interpretation. Genetic colocalisation helps identify candidate causal genes b...
journals.plos.org
Design and interpretation of eQTL-GWAS colocalisation studies: Lessons from a large-scale evaluation
Jeffrey Pullin