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Fantastic work coming out of Neil Hunter’s lab! www.nature.com/articles/s41...
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Conditional ablation experiments show that key components of the synaptonemal complex protect double Holliday junction recombination intermediates to ensure their resolution into crossover products, which are required for accurate chromosome segregation during meiosis.
www.nature.com
Protecting double Holliday junctions ensures crossing over during meiosis - Nature
Piotr Ziolkowski