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Glia biologist. Vision scientist. Interested in mechanisms of development and ageing in the retina. We love glia. You should too.
Ryan MacDonald







We’re hiring a new research fellow. Come join us in London to study glial cells in the ageing retina using killifish as a model. www.ucl.ac.uk/work-at-ucl/...
Feb 7, 2025
Ryan MacDonald
Excited to share our new manuscript from the Yoshimatsu and MacDonald labs. www.biorxiv.org/content/10.6.... We found that my favourite glial cells can regulate local retinoic acid signalling to specialise cone photoreceptors for high acuity visual function.
3mo
#ZebrafishCareers πŸ‡¬πŸ‡§ (Postdoc) #killifish
Feb 7, 2025
First post on this platform is to announce that our preprint is posted to bioRxiv: bioRxiv 2025.02.03.636318; doi: doi.org/10.1101/2025...
Feb 4, 2025
Ryan MacDonald
Zebrafish Rock!
Our work on the TET enzymes in retinal development is out. We identified that rod fate is inhibited when DNA demethylation is prevented by removal of the TET enzymes. Interestingly, photoreceptor numbers are normal. We utilized WGBS and bACE-seq to profile the precise localization of 5mC and 5hmC,…
Hi all, we got a grant for a cool project that will follow up of our paper published a few months ago (see below). We will explore how light acts as a morphogen to instruct PCP. If you are looking for a postdoc position and interested in this topic, please reach out!
10mo
11mo
Brian Clark
My lab studies mechanisms of pediatric glaucoma and the development of tissues affected (Schlemm's canal and trabecular meshwork). I am getting creative with fundraising because, well... So if you know someone who might be interested in funding our work: joinus.cuimc.columbia.edu/index.cfm?fu...
Mar 27, 2025
Brian Clark
#ZebrafishCareers πŸ‡¬πŸ‡§ (Postdoc) #killifish Link to MacDonald Lab website: zebrafishucl.org/macdonald-la...
Apr 3, 2025
Michel Cayouette
Zebrafish Rock!
Revathi Balasubramanian
Your Columbia is your opportunity to be a part of the unparalleled research, education, and clinical care that takes place every day at Columbia University Irving Medical Center. It’s a potent and imp...
joinus.cuimc.columbia.edu
I'm supporting Your Columbia!