Refined single-cell profiling captures a CCR5high CD4+ cytotoxic T-cell precursor in multiple sclerosis
www.thelancet.com/journals/ebi...
We show that low-frequency, circulating Th17.1 cells harbour a unique MS-associated
CCR5high cluster with enhanced cytotoxic and CNS-infiltrating potential. This CD4+
cytotoxic T-cell precursor could ...