If you have 16S long reads (e.g., plasmidsaurus data), this is an amazingly accurate and fast ASV caller. Of course it's another amazing program from @jimshaw.bsky.social
Alex Crits-Christoph
Sensitive long-read amplicon sequence variant recovery with savont https://www.biorxiv.org/content/10.64898/2026.05.26.727271v1