Very cool study! A very logical explanation for the fundamental question how non-stem cells “know” they need to become one after tissue damage. And is this deregulated in cancer?
Joris van de Haar, MD, PhD
📢 New preprint 🔥
1/ Stem cell regeneration is often viewed as an actively induced process, triggered by damage. But what if plasticity is actively suppressed by the stem cells themselves? We explored plasticity with 'new' cell type ablation tech in normal human colon organoids
tinyurl.com/3ky4ccxf
