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tries to make microscopes smarter · bioimage analysis, optogenetics, ml, 3d printing, open science · postdoc in cellular signalling dynamics @PertzLab · https://hinderling.github.io
Lucien Hinderling









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📣 Submission deadline extended for special issue "Taking the Stage: The Future of Microscopy"! The Journal of Microscopy has launched an open call for papers for an exciting new special issue which will feature submissions by Early Career Researchers. Deadline extended: 30 April 2026
How do epithelial cells integrate mechanical and biochemical signals to control their behavior? I am @ronjahoutekamer.bsky.social, and in this thread, I’ll show you how force transduction connects to biochemical signaling, and how it activates ERK by inducing biochemical ligand shedding.
1mo
2mo
epithelial mechanics fan club
Hi all fans of #smart #microscopy, we from @zeiss-microscopy.bsky.social have just published a new application note: "Study Mitotic Progression with Guided Acquisition – Rare Event Detection" go2.zeiss.com/ODk2LVhNUy03... For more details: forum.image.sc/t/applicatio...
2mo
say hello to Laurent! just started his PhD, and new on bluesky. cloning-wizzard and optogenetics-guru, using microscopy to link signaling & mechanics
How does an orbiting spherical tissue suddenly break symmetry and sprout invasive strands? We can predict this behavior from the initial morphology! Hi, I’m @jiwon-kim.bsky.social from @ianywonglab.bsky.social.
2mo
1mo
Video
Sebi
It's funky axons time 🔬 🧪
How do you know if a microscopy experiment can actually resolve a biological structure? Introducing VLab4Mic, a platform that predicts structural resolvability before you go to the microscope Led by Damián Martinez and Bruno Saraiva at @henriqueslab.bsky.social www.biorxiv.org/content/10.6...
Lucien Hinderling
1mo
5d
epithelial mechanics fan club
Spinning spheroids on 40 µm circular patterns. Recent work from @olivierpertz.bsky.social lab!
2mo
Video
🚨📰Now online in its full form www.nature.com/articles/s41...
2mo
Mario Del Rosario
Our thread is now up at @epimechfc.bsky.social 💗 Take a look if you are interested in how a living tissue knows how to sculpt itself!
Laurent Dubied
Christophe 🔬 Leterrier
1mo
Tracking fast molecules in crowded organelles is error-prone, obscuring dynamic processes like Alzheimer’s secretase activity or secretory sorting. Here, authors present FidlTrack, a structure-aware m...
www.nature.com
FidlTrack: high-fidelity structure-aware single particle tracking resolves intracellular molecular motion in organelles sensing APP processing - Nature Communications
How does an orbiting spherical tissue suddenly break symmetry and sprout invasive strands? We can predict this behavior from the initial morphology! Hi, I’m @jiwon-kim.bsky.social from @ianywonglab.bsky.social.
1mo
Avezov lab
Video
epithelial mechanics fan club
Our new paper's out: FidlTrack—structure-aware single-particle tracking benchmarks/boost SPT fidelity With it we resolve with sub-organelle res. e.g. BACE1 amyloidogenic APP cleavage #Alzheimers, ER exit events, map nanobody binding in realtime in ER/organelles 🔬🧠#SingleMolecule rdcu.be/e3Ris
3mo
Video
Jiwon Kim
Avezov lab
Make your own PDMS+micromirror device for single-objective light-sheet SMLM: www.biorxiv.org/content/10.6...
1mo
Christophe 🔬 Leterrier