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USC's Stevens Neuroimaging and Informatics Institute (INI) applies innovative imaging and information technologies to studying the brain. We share our data and resources with thousands of collaborators around the world. Home of Lab of Neuro Imaging (LONI).

USC INI

Our NEW visualization highlights several major white matter pathways, including the arcuate fasciculus, cingulum, superior longitudinal fasciculus, and uncinate fasciculus. These bundles help support essential functions such as language, memory, attention, emotion, and cognition.

How is bipolar disorder reflected in the brain’s communication networks? Our new study in Biological Psychiatry used diffusion MRI and ENIGMA data from 16 international sites to map subtle but widespread brain network differences tied to illness severity and treatment exposure. bit.ly/4eaT6Dk

Our Spring Newsletter is here 🌱 Catch up on the latest, including new research on Alzheimer’s risk and stroke recovery, faculty honors, AI-driven discovery, student training, and more. Read the full issue: bit.ly/43hD7yb

After optic nerve injury, gentle electrical stimulation can help guide damaged nerve fibers as they regrow and reconnect with the brain. This research could help advance future treatments to repair neural connections damaged by disease or injury 👀 🧠 www.youtube.com/watch?v=l3xB...

This animation shows blood flow in a patient with a grade IV glioblastoma. Using a 7T MRI technique called arterial spin labeling, we can see areas of uneven blood supply within the tumor. Regions with higher blood flow likely indicate faster-growing cancer.

Marco Ebeling will be conducting research on restoring vision using neurotechnology under the supervision of Drs. Eduardo Fernández and Gema Martínez-Navarrete at the Universidad Miguel Hernández de Elche in Elche, Spain. Congratulations, Marco!!

👀 👀 Our 3D reconstruction from an MRI scan reveals the major pathways that connect different regions of the brain. The colors show the direction of each fiber bundle: red runs left to right, blue runs top to bottom, and green runs front to back.

The brain’s wiring changes across a lifetime. Now, we have a clearer map 🗺️ 🧠 In a study published in @nature.com Communications, our researchers built one of the largest models of white matter, helping detect brain changes linked to aging and disease. Learn how: bit.ly/4uEOb4o

Our digital, interactive 2025 Annual Report is live! This year’s report highlights our advancements in AI-powered brain research, imaging innovation, large-scale global collaborations, and training the next generation of neuroimaging and informatics leaders. Read the full report: bit.ly/4veK3YN

Throwback animation 👀 🧠 Dr. Kay Jann and his team found that people with Alzheimer’s show less complex brain activity at rest. This change was linked to higher tau buildup and poorer cognition, suggesting brain signal complexity could help detect and track AD earlier. www.youtube.com/watch?v=wb8D...