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Join us 📆 9 Dec ⏰ 12.45 @tb-lshtm.bsky.social seminar Free & Open to all @kchorton.bsky.social @richardwhite321.bsky.social @reinhouben.bsky.social @dopapus.bsky.social @laragosce.bsky.social @danieljgrint.bsky.social tinyurl.com/2s4y3jcd
Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...
@lshtm-tbmod.bsky.social is offering multiple PhD opportunities through MRC LID, deadline 14 Jan. More details: mrc-lid.lshtm.ac.uk/applicants/ Projects include #1 TB & screening #2 TB & climate change #3 TB & vaccines #4 TB & influenza #5 TB & prevention @cmmid-lshtm.bsky.social @lshtm.bsky.social
Understanding patterns of #TB exposure and transmission is needed for targeted prevention strategies. In our latest pre-print, @petedodd24.bsky.social and I estimated the proportion of TB exposure to and transmission from sex and age groups for 177 countries. bit.ly/4nbV492
Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...
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3d
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In a new preprint (NOT PEER REVIEWED) we continue to explore the challenge of overtreatment in community screening. It seems the benefits of TB treatment far outweigh the harms, especially once we accept that sputum culture is not perfect. Important food for thought. www.medrxiv.org/content/10.1...
“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...
When fluoroquinolone resistance status is unknown, empirical use of BPaLM (adding moxifloxacin to BPaL) is cost-effective as a replacement for BPaL even with high fluoroquinolone resistance levels! 🦠💊 doi.org/10.1371/jour...
At a time when global resources for #TB research, development, prevention, and care are limited, which interventions should be prioritised in high burden settings? 📢 Our new pre-print compares the impact, cost, and cost-effectiveness of 9 TB interventions in 3 countries. 1/n bit.ly/3V3vXth
Each year, many LSHTM TB researchers participate in the UNION World Conference on Lung Health, the world's largest conference on TB and lung health. This year, the conference takes place in
tinyurl.com
Excerpts from Copenhagen: The UNION World Conference on Lung Health 2025
Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…
www.sciencedirect.com
Cost-effectiveness of conditional cash transfers with pre- and post-test tuberculosis counselling in South Africa: a modelling analysis
MRC LID studentship information for applicants How to Apply Projects Studentship funding Studentship options Studentship...
mrc-lid.lshtm.ac.uk
Information for applicants - MRC London Intercollegiate Doctoral Training Partnership Studentships
8mo
Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...
www.thelancet.com
Climate change and tuberculosis: an analytical framework
Tuberculosis (TB) is a major public health concern and the leading infectious cause of mortality globally. The disease exhibits strong prevalence patterns by age and sex, but the implications of these...
www.medrxiv.org
A global analysis of patterns of tuberculosis exposure and transmission
7mo
7mo
9mo
Lara Goscé
TB Centre LSHTM
Finn McQuaid
Finn McQuaid
Another successful "Intro to TB Modelling" course in Copenhagen at #WLHC2025. Over 70 joined to learn about TB modelling! Followed by the now-traditional TB Modelling and Analysis Consortium social, which was also very well-attended and a lot of fun.
Background Community-wide screening is a crucial strategy to end tuberculosis (TB), but a common concern is potential harm from overtreatment following false positive diagnoses. However, current refer...
www.medrxiv.org
Do no harm - re-evaluating the risks of overtreatment in community-wide tuberculosis screening
Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...
www.thelancet.com
Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative
The WHO recommends the bedaquiline, pretomanid, and linezolid (BPaL) regimen with the additional fluoroquinolone antibiotic moxifloxacin (BPaLM) for initial treatment of multidrug- or rifampicin-resis...
doi.org
Impact of fluoroquinolone resistance on the cost-effectiveness of empiric treatment for multidrug- or rifampicin-resistant tuberculosis
Background While a range of interventions exist for tuberculosis prevention, screening, diagnosis, and treatment, their potential population impact and cost-effectiveness are seldom directly compared,...
bit.ly
The potential impact, cost and cost-effectiveness of tuberculosis interventions - a modelling exercise
Katherine Horton
6mo
Katherine Horton
Matthew Saunders
Rein Houben
Richard White