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arxiv.org/abs/2606.05474
11d
Protein binder design has largely optimized for affinity alone, leaving conformational selectivity unaddressed: for allosteric targets such as kinases, nuclear receptors, and GPCRs, a binder that enga...
arxiv.org
AlloGen: Conformation-Selective Binder Generation with Differential State Scoring
Filippo Caschera
