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Check out the phenomenal PhD work by Katie Copley, a current postdoc in our lab @yaleneuro.bsky.social @yalerna.bsky.social. www.science.org/doi/10.1126/...
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Aberrant aggregation of the prion-like RNA binding protein TDP-43 drives several fatal neurodegenerative proteinopathies, including amyotrophic lateral sclerosis (ALS). In this work, we define how sho...
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Short RNA chaperones promote aggregation-resistant TDP-43 conformers to mitigate neurodegeneration
Junjie Guo