New in @natgenet.nature.com by @asifa-akhtar.bsky.social lab.
BRD2 & BRD4 control different steps of transcription, yet most BET inhibitors target their shared bromodomain – hitting both at once & producing effects that are hard to predict.
Why it matters for cancer
www.nature.com/articles/s41...
Max Planck Institute of Immunobiology and Epigenetics