Happy to share our perspective on Mechanobiology across scales! This started as a stimulating discussions at the N4M conference, Camogli 2 years ago and culminated through lots of discussions, edits and co-working!Special thanks to Daniel Müller and his lab for coordinating and driving this work 🍾📣
If you've been wondering what our current obsession with OME-Zarr and lego blocks is about, I have good news for you: the Fractal preprint is out!
Thanks to @joelluethi.bsky.social , all co-authors, and the Fractal developers and users community for making this beautiful project a reality ❤️
NEXT TUE: DDD seminar, Jan. 27, 2025 @ 1PM Eastern US: Nadezhda Azbukina @nazbukina.bsky.social (from Dr. Barbara Treutlein's group) will speak on "A systematic study of morphogen patterning and its reproducibility in human neural organoids". carlocolantuoni.org/seminar
Checkout this updated preprint-a tour de force and truly globe-spanning collaboration with an exceptional group of scientists.
1/ 🚀🧪🤖 Big update for #Omega — the LLM-powered autonomous agent for bioimage analysis in @napari.org ! Custom LLM endpoints, layer actions, plugin extensibility, agentic widget maker, modernized UI, & 30+ fixes. Here's what's new in version *2026.2.8.2*:
Jain_Akanksha_
Virginie Uhlmann
How does an ovarian follicle remodel in space and time to release an egg? 💥🥚
We have an exciting PhD project combining follicle culture, advanced imaging and quantitative analysis to understand the cellular dynamics of ovulation. 🔬
Co-supervised by me and @guignardlab.bsky.social. Please share! 🌱
Carlo Colantuoni
Video
Open-source atlas of fruit fly development DynamicAtlas is a high-res framework for morphological studies
📹 M. F. Lefebvre, V. Jain-Sharma, N. Claussen & N. P. Mitchell et al @streichan.bsky.social lab University of California Santa Barbara in @natmethods.nature.com
➡️ bpod.org.uk/archive/2026...
And here is the link to access the whole pdf. Enjoy!
I strongly believe that focusing on information & computation during Development provides an important framework, that encapsulates the genetic, chemistry & mechanics, but focusses on organisation, dynamics & logic.
PDF: tinyurl.com/4hn34t8w
These images show live embryos of animals (jellyfish, crustacean, worm, sea urchin, sea squirt, beetle) and one of animals closest single-celled relatives. They were captured taking advantage of fluorescent proteins localised on the outer membrane of cells, allowing us to observe cell outlines. 1/9
In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...
Loïc A. Royer 💻🔬🧪
Murawala Lab at MDI Bio Lab
This link will take you to a page that’s not on LinkedIn
We’re excited to share our latest preprint on Fractal: our approach towards FAIR bioimage analysis at scale with OME-Zarr-native workflows.
Fractal defines interoperable tasks on OME-Zarr and provides a platform for TB-scale image analysis.
(1 / 10🧵)
www.biorxiv.org/content/10.6...
Christopher Thomas
Biomedical Picture of the Day BPoD
Thomas Lecuit
Nature Nanotechnology, Published online: 11 June 2026; doi:10.1038/s41565-026-02179-0The Perspective highlights key challenges in mechanobiology, including the need to engineer multicellular reference models, develop and refine biophysical methods to manipulate and quantify biomechanical properties across scales and establish theoretical frameworks to interpret complex mechanobiological phenomena.
