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X-ray diffraction data were collected at @esrf.fr on various MX beamlines. Thanks to @dfg.de @uni-freiburg.de @uniklinik-fr.bsky.social @cibss.bsky.social for the funding
4mo
Christophe Wirth
Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1. ⬇️ www.sciencedirect.com/science/arti...
5mo
www.sciencedirect.com
The renal solute carrier URAT1 (SLC22A12) is essential for urate homeostasis, with loss-of-function linked to renal hypouricemia, nephrolithiasis and …
Molecular Determinants of Selective and High-affinity Binding of the Scaffold Protein PDZK1 to the Urate Transporter URAT1
Christophe Wirth
🚨 Paper Alert! In this new work published in @jcellsci.bsky.social we shift our focus on MTFR1L and the feedback loop linking mitochondrial fission, mitophagy and apoptosis. MTFR1L emerges as a critical coordinator of the fission and autophagy machinery. 🔗Find the paper here: doi.org/10.1242/jcs....
2mo
Claudine Kraft's Lab
Happy to share our paper in the frame of the @sfb1453.bsky.social project that got published in @jmolbiol.bsky.social Tremendous work from @emymrikov.bsky.social and others, on how the scaffold protein PDZK1 interacts with the urate transporter URAT1. ⬇️ www.sciencedirect.com/science/arti...
5mo
The renal solute carrier URAT1 (SLC22A12) is essential for urate homeostasis, with loss-of-function linked to renal hypouricemia, nephrolithiasis and …
www.sciencedirect.com
Molecular Determinants of Selective and High-affinity Binding of the Scaffold Protein PDZK1 to the Urate Transporter URAT1
Christophe Wirth