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Online Now: SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell types Online now:
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Anerillas et al. generated SenCat, a multi-omic atlas of senescence across diverse human cell types, revealing no universal markers but conserved damage-response and metabolic pathways. Machine-learning-derived signatures robustly recognize and quantify senescence across datasets, tissues, and species, providing a broadly applicable framework for identifying senescent cells in vivo.
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SenCat: Cataloging human cell senescence through multi-omic profiling of multiple senescent primary cell types
Molecular Cell