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Online Now: A time-resolved atlas of histone modifications during mitotic entry Online now:
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DNA is wrapped around histones, forming chromatin, which becomes more compact during mitosis. Kochanova et al. elucidate the complex landscape of histone post-translational modifications upon mitotic chromosome formation and discover that H3T3ph is restricted to chromatin with silent genes and that acetylation is only mildly decreased as chromosomes form.
A time-resolved atlas of histone modifications during mitotic entry
Molecular Cell