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“NIH researchers found that exercise triggers mitochondrial DNA release in muscle, activating immune pathways that boost fat-burning fibers and fight obesity—but this same response may worsen fatigue in long COVID and #ME/CFS through immune overactivation.” www.cell.com/trends/endoc...
Jun 13, 2025
Exercise-induced inflammation is regarded as a response to muscle damage from mechanical stress, but controlled immune signaling can be beneficial by promoting metabolic adaptation which, for example,...
www.cell.com
Mitochondrial innate immune signaling in skeletal muscle adaptation to exercise