In Lausanne, we have an incredible environment for research, and our immunology hub is truly thriving! I’m proud to be part of it 👇
PAPER ALERT!
I am excited to share that our study describing the molecular mechanism of caspase-4 activation has just been published in Immunity.
www.cell.com/immunity/ful...
I would like to thank all the co-authors for their valuable contributions.
Well done guys!
Link for short summary below👇
Jakub Began
The cytosolic LPS sensor caspase-4 controls antibacterial immunity by inducing pyroptosis
and cytokine secretion. Began et al. show how remodeling of LPS membranes by interferon-induced
GTPase GBP1 pr...
Finishing up in snowy Banff with current and former Broz Lab members after the innate immunity symposium. @jakubbegan.bsky.social @kaiwenchen-lab.bsky.social @ehartenian.bsky.social @keystonesymposia.bsky.social
Broz Lab
Excited to share this paper from @yiechanglin.bsky.social showing how lipids can move between bacterial membranes along the bridge like protein TamB. Also happy to be able to post the cool movie. 🎥🌟 #MDsimulations #StructuralBiology doi.org/10.1016/j.bp...
Video
I am excited to share that our study describing the molecular mechanism of caspase-4 activation has just been published in Immunity.
https://lnkd.in/e68uHHAA
I would like to thank all the co-authors...
🔥Did you know that the inflammasome was discovered in Lausanne?
This groundbreaking discovery in cell signaling was led by Jürg Tschopp’s group at the University of Lausanne (@unil.bsky.social). 🧵(1/9)
