Small molecule LC/MS specialist. https://biryb.github.io/
I'm a creator and author at Bioanalytical Bees - tutorials and deep dives on all things LC/MS for the newbies and newbie-minded: https://bioanalytics.substack.com/
Birgitta Ryback
A little late to Blusky but first things first: Join us at Metabolomics of Boston if you work on small molecule mass spectrometry! Come for the talks, stay for the people (& snacks, but maybe that's just me)
Thursday this week btw! Food>date with limited characters
What are internal standards and how exactly do we use them to correct for experimental hiccups? Shedding light on this important application of labelled metabolites.
bioanalytics.substack.com/p/what-are-i...
Need a reference database for metabolite profiling? Training an ML model on chemical structures? Pubchem is the world’s largest chemical database, @pola.rs streaming engine lets you wrangle it on your laptop.
bioanalytics.substack.com/p/processing...
#cheminformatics #bioinformatics #Chemsky
Important MOB talk coming up: A tutorial on depositing data to Metabolomics Workbench. I’ll admit: I only do it when a journal requires it, and I don’t usually go the extra mile with metadata. Hoping this seminar changes my ways!
(Also, there’s free food 😊)
www.moboston.com/about
#metabolomics
Ever wonder how to figure out a molecule’s formula just from its mass?
In today’s edition of Bioanalytical Bees, I break down how to ID compounds from scratch - no library, no MS2, just some mass spec magic.
bioanalytics.substack.com/p/identifyin...
#metabolomics #lcms
In untargeted (metabol)omics, we don’t know what we’re looking for, so how do we optimize separation while maximizing metabolite coverage?
Check out this post for some practical chromatography tips I wish I’d known earlier: bioanalytics.substack.com/p/optimizing...
#metabolomics #lcms
Our paper showing that ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST is now published @cp-cellmetabolism.bsky.social
Thanks to everyone involved!
www.cell.com/cell-metabol...