This is the big one! So proud to have played a part on this team.
www.science.org/doi/10.1126/...
Enlicitide is an exciting potential molecule for cardiovascular disease, but if we were going to make it on a commercial scale, existing chemical techniques just weren't going to cut it.
Historically, many compelling therapeutic targets have been accessible only by injectable biologic drugs. Macrocyclic peptides, such as the proprotein convertase subtilisin/kexin type 9 inhibitor enli...