Cells in crowded epithelia aren’t chosen at random for extrusion & death — energy levels decide who goes. Great work from Jody Rosenblatt and team shows cells with low energy stay depolarized, triggering K⁺ and Cl⁻ channels, lose water, shrink, and are extruded alive. www.nature.com/articles/s41...
www.nature.com
Crowded epithelial cells with the least energy and membrane potential are selected for extrusion.
