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"Here we show that heartbeat sound promotes structural and functional maturation of human cortical organoids with a physiological astrocyte-to-neuron ratio." 🤯 www.biorxiv.org/content/10.1...
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Heartbeat sound is one of the first rhythmic stimuli encountered by the developing human brain, yet its biological role has remained unexplored. Here we show that heartbeat sound promotes structural a...
www.biorxiv.org
Astrocytic PIEZO activation by heartbeat sound promotes extracellular matrix and maturation in human brain organoids
Sébastien Gauvrit