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Plants use immunogenic peptides to coordinate immunity. Pathogens can mimic them to hijack defense. 🌱 We compare phytocytokines with animal cytokines and ask how these signals are made, released, mimicked, and controlled in space and time. doi.org/10.1111/tpj....
Delighted to see this work out in #ScienceAdvancesResearch @science.org where we uncover a surprising evolutionary origin of fungal effector proteins as ancient antimicrobials. Led by the super-star @mesny.bsky.social in the frame of @ceplas.bsky.social @mibinet.bsky.social & @madfungi.bsky.social
Thank you to @izzysaurlab.bsky.social, @teamthomma.bsky.social, and their teams for hosting our next two MadFungi workshops, "Expression in Barley Protoplasts" and "Expression of Antimicrobial Proteins," at @unicologne.bsky.social. It was a great week with all of our MadFungi PhD candidates! 🍄
So diverse and yet conserved. Check out opinion paper by Leonhard Pachinger @leopach.bsky.social on antimicrobial effectors produced by fungal pathogens: www.sciencedirect.com/science/arti...
What enables a fungus to invade a mammal host? @marco-guerreiro.bsky.social unravels signatures of translation adaptation among pathogenic and non-pathogenic species of Trichosporonales. See more: www.nature.com/articles/s41...
Our PhD candidates are having a great time at the MadFungi transcriptomics workshop at the University of Kiel @uni-kiel.de. Special thanks to @estukenbrock.bsky.social and her team for the great organization!
Check this out👇 New from the Doehlemann lab! A fungal enzyme modulates plant-microbe and microbe-microbe interactions 🔥
Where do plant pathogen effectors come from? @mesny.bsky.social shows how fungi turned shield 🛡️ into sword ⚔️ to end up with dual-function molecules to disrupt host immunity & protective host microbiota. @ceplas.bsky.social @mibinet.bsky.social @madfungi.bsky.social www.science.org/doi/10.1126/...
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Antimicrobial effectors of plant-associated fungi: multipurpose proteins with fast-evolving surfaces and structurally conserved cores
Plants are exposed to a variety of devastating pathogens, causing significant yearly yield losses. In order to facilitate infections, plant pathogens …
www.sciencedirect.com
Emerging fungal pathogens have detrimental impacts on crops, animals, and humans, however little is known about their transition to a pathogenic lifestyle. This study demonstrates that the transition ...
www.nature.com
Genomic and physiological signatures of adaptation in pathogenic fungi - Nature Communications
Fungal effectors may have evolved from ancient antimicrobials, shaping plant microbiota and immunity during infection.
www.science.org
Plant-associated fungi co-opt ancient antimicrobials for host manipulation
MadFungi
Maurice König
MadFungi
Eva Stukenbrock
Eva Stukenbrock
MadFungi
Team Thomma
Johana Misas Villamil
Team Thomma
Proud to share our new paper on how prion-like fungal effectors target plastids and modulate host metabolism during root symbiosis. Exciting collaborative work uncovering PEPSI effectors and the interaction of one of them with DXR in plants. www.biorxiv.org/content/10.6... bsky.app/profile/eell...
GH25 lysozyme mediates tripartite interkingdom interactions and microbial competition on the plant leaf surface https://www.biorxiv.org/content/10.1101/2025.04.04.647216v1