Nice work adding to the mounting evidence that the ON-OFF division is not so straightforward. It could explain why we could change the ON-OFF selectivity of ganglion cells by changing the visual context in this paper: www.nature.com/articles/s41...
www.nature.com
Ganglion cells classically respond to either light increase (ON) or decrease (OFF). Here, the authors show that during natural scene stimulation, a single ganglion cell can switch between ON and OFF d...
How is the ON and OFF pathway split in the visual system? 🤔
The textbook standard, that bipolar cells are separated simply by the glutamate receptors they express, might be due for an update....a short 🧵
