Assistant Professor of Applied Physics @Stanford. Theoretical biophysics, evolutionary dynamics & microbial evolution. https://bgoodlab.github.io/
Ben Good
Loading...
Check out our newest pre-print about E. coli and phage evolution when the gut is on 🔥! It will only take 20 minutes to read the main text.
#PEQG26 folks! I will be presenting my postdoc project with @jkpritch.bsky.social and @jeffspence.github.io about inferring population structure dynamics over time with tensor decomposition on ARG. The talk will be at the James Crow Talk session on Wednesday. Look forward to seeing everyone there!
I’m looking to hire one or two postdocs - possible projects include pop gen theory, methods development, and human evolutionary inference. Please share, and email if you are interested.
More info: evoldir.net/brian/evoldi...
in case you missed it: profmcinerney.substack.com/p/the-pangen... "The Pangenome Is Not A Parts List"
Can we use ecological principles to increase coexistence in synthetic bacterial communities? Our new paper is now out in @isme-microbes.bsky.social: "Environmental complexity shapes maintenance of bacterial diversity through context-dependent interactions among niche axes" doi.org/10.1093/isme...
We're launching a major collaborative Center aimed at accelerating phage therapy @gladstoneinst.bsky.social. High-throughput experiments with engineered phages (my lab) and strains (Silas Lab), organoids (Ott Lab), and AI (Pollard Lab).
gladstone.org/news/gladsto...
Evolution induced state shifts in a long-term microbial community experiment (now out, but previously posted here as a preprint) with Ville Mustonen, Lutz Becks @jcairns.bsky.social & others. Experiment continues @utu.fi and now 5+ years www.pnas.org/doi/10.1073/...
I’m honored to be selected as one of Scientific American’s inaugural Young American Scientists, a recognition of 28 early-career researchers whose work is shaping the future of science. My interview is here: www.scientificamerican.com/article/trev...Â
#SciAmYoungScientists @sciam.bsky.social
Now published: journals.plos.org/plosbiology/...
evoldir.net
Yun Deng
The pangenome is the total genetic repertoire of a group of organisms. It is a property of populations, maintained by evolutionary processes.
Spent the last two years developing a new Intro to Physics course for undergrad biology majors. It features tons of examples from biology (especially Ecology & Evolution!) and requires only middle school-level math. Lecture note here shorturl.at/0PiVp
Any comments or feedback are highly welcome!
Biological communities are complex, dynamic systems that underpin ecosystem functionality,
yet their long-term dynamics and predictability remain p...
Mutation rates per generation are strikingly similar across germlines of animals and across at least one somatic cell type, suggesting a key role for natural selection in shaping mutation rates. This ...
journals.plos.org
Seth Shipman
Abstract. Microbial communities are often more species-rich than predicted from classical ecological models. The high levels of coexistence observed in nat
Happy to highlight an essay I wrote together with @marcdemanuel.bsky.social,
@natanaels.bsky.social and Anastasia Stolyarova, trying to think through what sets the mutation rate of a cell type in an animal species: www.biorxiv.org/content/10.6... 1/n
The center, funded by an NIH grant, will become one of three national centers dedicated to accelerating the development of phage therapy.
Germline mutation rates per generation are strikingly similar across animals, despite vast differences in life histories. Analogously, in at least one somatic cell type, mutation rates at the end of l...
🧵 New preprint out! We asked: what happens to gut bacteria when the intestine is under chronic inflammation (IBD)? Turns out, the host's inflammatory state reshapes how they evolve, and the results are pretty striking. A thread 👇
