Just in time for under the Christmas tree🎄our paper on Friedel-Crafts acylation of bicyclo[1.1.1]pentane ketones out in @JOC_OL pubs.acs.org/doi/10.1021/.... Great work by Karolina and Freya; collaboration with #PavelMykhailiuk @EnamineLtd. Funded by @researchireland.ie @tum.de ‪@ias-tum.bsky.social
Bicyclo[1.1.1]pentane (BCP) is a rigid aliphatic hydrocarbon with a three-dimensional (3D), propeller-like shape and a molecular size that makes it a targeted bioisosteric replacement for phenylene an...
