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by @danabra.mov
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by @danabra.mov
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by @jimpick.com
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by @atsui.org
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Now up, led by Ashton Omdahl! Our method GLEANR finds shared genetic factors across lots of GWAS, and handles spurious correlation driven by cohort overlap. Neat examples of factors driving related traits with enrichment in different cell types / developmental stages.
10mo
Alexis Battle
📣New from @alexisbattle.bsky.social & co! 📄Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components
10mo
We developed a computational method to identify genetic pathways shared among complex traits that applies matrix factorization to decompose genetic associations across hundreds of phenotypes. Our meth...
www.cell.com
Sparse matrix factorization robust to sample sharing across GWASs reveals interpretable genetic components
The American Journal of Human Genetics