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Zabala-Letona et al. here: www.nature.com/articles/s41...
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www.nature.com
Polyamines prevent the action of kinases on acidic phosphorylatable motifs in spliceosomal proteins, thus providing a mechanism for metabolite-mediated regulation of alternative splicing in cells.
Polyamine-dependent metabolic shielding regulates alternative splicing - Nature
Maya Emmons-Bell