Normally writing papers exhausts me, but working on this brought such joy. A very exciting study from Mckenna linking errant estrogen signaling with gut defects in NOD2-deficient fish.
journals.plos.org
Crohn’s disease is associated with mutations in the innate immune receptor NOD2, but the mechanisms underlying NOD2 regulation of intestinal homeostasis remain unclear. This study shows that NOD2 inte...
