You have no idea how proud I am of of this paper from the lab showing that RANK signalling affects the development of Tuft and BEST4 cells in the zebrafish gut, with in vivo evidence indicating that BEST4 cells contribute to defences against enteropathogens
Here they provide evidence that RANK signaling contributes to specification of intestinal epithelial tuft and BEST4 cells, and that loss of RANK impairs the ability of the host to navigate infections ...
