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A case study of a 22-year-old patient with cystic fibrosis and identified for phage therapy, found pre-existing phage antibodies. These antibodies may have contributed to clinical failure by effectively neutralizing the phage. www.nature.com/articles/s41... @jeremyjbarr.bsky.social
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A 22-year-old patient with cystic fibrosis and chronic, drug-resistant Bordetella bronchialis infection received compassionate-use phage therapy. Serum samples revealed that pre-existing antiphage imm...
www.nature.com
Cross-reactive anti-prophage antibodies and bacterial heteroresistance implicated in phage therapeutic failure - Nature Medicine
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