How much of the human genome is essential?
Two pieces out today from our lab: 1) a method to map essential genomic intervals at gigabase scale, and 2) an argument that it's time to consider synthesizing a minimal human genome.
biorxiv.org/content/10.6...
nature.com/articles/d41...
Sudarshan Pinglay
A decade on from the launch of an ambitious project, it’s time to revisit the reasons for constructing a human genome from scratch.