I am skeptical that already approved Ebola virus vaccines and monoclonals will show promise during the ongoing outbreak of Bundibugyo virus for the simple reason that the two viruses are highly divergent (~35% AA divergence in GP).
Focus should be on BDBV-specific or "pan-Ebola" countermeasures.
🧵
Kristian G. Andersen
"It’s worth doing a clinical study, but I think the idea that, like, ‘Oh, let’s just roll out Ervebo and then hope for the best’ is misguided."
cen.acs.org/articles/104...
