If you are interested in high-throughput calibration, take a look at the acmgscaler R package:
cran.r-project.org/web/packages...
Or plug in your MAVE or VEP of interest to our Colab:
colab.research.google.com/github/badon...
Provides a function to calibrate variant effect scores against evidence strength categories defined by the American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pa...
