It's been a while time to give #immunology @bsky.app another go...Thrilled to share work led by Dr Yuki Keith & colleagues @garvaninstitute.bsky.social, UNSW & Melanoma Institute Australia now out @jem.org. CD169+ macs in skin surround & constrain melanoma growth independent of T and B cells! 1/2
Tissue-resident CSF1R-dependent CD169+ macrophages localize deep in the skin. They surround growing tumors and directly suppress their growth independent o