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🚨 Paper alert! What if you could eavesdrop on a neuron's electrical dynamics without ever breaking in? Our new study uses DNA origami tiles that self-insert into live neuronal membranes, even dendrites, to form stable ion channels. In fact, even repeated intracellular access from the same cell 🧬⚡
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Self-inserting DNA origami tiles form stable nanopores across live neuronal membranes, enabling intracellular-like voltage recordings, small-molecule delivery and access to hard-to-reach dendrites wit...
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Intracellular neuronal recordings across DNA tiles - Nature Nanotechnology
Krishna Jayant
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Intracellular neuronal recordings across DNA tiles
Nature Nanotechnology, Published online: 01 June 2026; doi:10.1038/s41565-026-02180-7Self-inserting DNA origami tiles form stable nanopores across live neuronal membranes, enabling intracellular-like voltage recordings, small-molecule delivery and access to hard-to-reach dendrites without membrane rupture.
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Nature Nanotechnology