🔬 New publication in Cancer Cell:
"Pathogenesis of diffuse large B cell lymphoma proteogenotypes"
Congrats to Julius C. Enssle, Björn Häupl, Arber Qoku, Florian Buettner, Louis M. Staudt, Thomas Oellerich and the entire research team!
👇 Read more here:
Frankfurt Cancer Institute
Online Now: Pathogenesis of diffuse large B cell lymphoma proteogenotypes
dlvr.it
Enssle et al. perform transcriptomic and proteomic profiling of diffuse large B cell lymphoma (DLBCL), revealing seven proteogenotypes (PGs) that reflect molecular and tumor microenvironment features across genetic DLBCL subtypes. PG4 identifies high-risk DLBCLs with diverse mutational profiles characterized by enhanced MYC and B cell receptor activity and exhausted T cells.