Excited to share that our AzoTag paper is now out in @natchem.nature.com! 🥳
We demonstrate de novo chemo-optogenetics through the rational design of photoresponsive small molecules and selection of their artificial protein binding pairs.
www.nature.com/articles/s41...
Optical manipulation of proteins is central to modulating and characterizing biomolecular functions in cell biology, but tools based on natural proteins are difficult to reconfigure for desired photoc...
