PI @ UT Southwestern. We build open-source microscopes + image analysis for rare cancer biology: navigate, Altair, autonomous microscopy, metastatic colonization.
https://www.dean-lab.org
https://thedeanlab.github.io
Kevin Dean
Very excited to be sharing our new paper, just out in Nature Cell Biology!
The big question we investigate: How do migrating cells put their front 🔴 and back 🔵 in the right place?
We’re hiring an optical systems engineer / scientist to help build and disseminate Altair, our open, modular light-sheet microscopy platform.
Ideal for someone with serious hands-on experience in optical design, Zemax, CAD, alignment, and microscopy.
Apply here: www.linkedin.com/jobs/view/44...
We got multiple times the feedback that oblique plane microscopes are too complex.
So how about a detection train with only two photographic lenses?
www.biorxiv.org/content/10.6...
🔬🔦In this Imaging spotlight, Kevin Dean @kevin-dean.bsky.social and team tell us about their motivation for designing Altair-LSFM, describe its key features, how to setup and use the system and their planned developments.
focalplane.biologists.com/2026/03/09/i...
Video
Photon unlimited contrast. Axially swept light-sheet microscopy using scattering and fluorescence contrast mechanisms. www.spiedigitallibrary.org/conference-p...
Altair Direct View OPM Preprint!
We built a simplified direct-view oblique-plane microscope for imaging big, optically accessible specimens with a single-objective light-sheet geometry. Delivers...
• ~5.4 mm field of view
• ~2.6 μm, ~3.4 μm, and ~17.8 μm resolution in X/Y/Z
Some great tutorials here! www.youtube.com/@LiveCellIma...
Some stars burn bright, and go dark too soon. Take care of yourself, and seek help when you need it.
Data bite: Why science is becoming less innovative
www.economist.com/the-world-in...
from The Economist
It’s a Commodore weekend.
Posted 11:44:16 AM. The Dean Lab in the Lyda Hill Department of Bioinformatics at UT Southwestern Medical Center is…See this and similar jobs on LinkedIn.
We are leaders of two NIH-funded research centers with national outreach in cancer cell imaging (grants RM1GM145399 and U54CA268072). This channel provides demonstrations and tutorials for the u-quant...
Altair Direct View OPM Preprint!
We built a simplified direct-view oblique-plane microscope for imaging big, optically accessible specimens with a single-objective light-sheet geometry. Delivers...
• ~5.4 mm field of view
• ~2.6 μm, ~3.4 μm, and ~17.8 μm resolution in X/Y/Z
