Dissecting the cellular architecture of breast cancer brain metastases reveals prognostically distinct immune landscapes
Breast cancer brain metastases are a dismal condition, and it is unclear which patients benefit from immunotherapy. Jassowicz et al. multimodally characterize the cellular architecture of 156 human breast cancer brain metastases. They unravel inter-patient immune heterogeneity and discover and validate biomarkers for prognostically relevant immune landscapes.
