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The results of a study in Nature Metabolism establish hyperglycosylation as a pathological driver of Alzheimer’s disease and highlight glycan metabolism as an actionable target in the fight against the disease. #alzsky #Neuroskyence 🧪
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Through spatial multiomics, spatial stable isotope tracing and retrospective cohort analyses, this study identifies hyperglycosylation as a driver of Alzheimer’s disease and a promising therapeutic target.
Hyperglycosylation is a metabolic driver of Alzheimer’s disease - Nature Metabolism
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