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Final version of our last paper is out! www.nature.com/articles/s41...
Excited to share our new paper out today in @science.org 🎉 We show that HGT via natural competence drives diversification of chromosomal integrons in V. cholerae đŸ€© Below a đŸ§” on key findings incl. background on natural competence in V. cholerae 1/ #microsky #phagesky www.science.org/doi/10.1126/...
Our lab is proud to present our latest work harnessing Bridge Recombinase for genome-scale editing in diverse bacteria, microbiome editing, and programmable horizontal gene transfer.
3mo
2mo
1mo
Inactivation of chromosomal genes through plasmid-encoded IS elements is an extended mechanism of antimicrobial resistance evolution in bacteria.
www.nature.com
Plasmids promote antimicrobial resistance through insertion sequence-mediated gene inactivation - Nature Microbiology
www.science.org
Cress Lab
Melanie Blokesch
Alvaro San Millan
Bridge recombinase enables versatile rewriting of bacterial genomes https://www.biorxiv.org/content/10.64898/2026.04.29.721476v1
Reversible DNA condensation drives natural transformation @natcomms.nature.com from Keith Mickolajczyk, Matthew Neiditch, and David Dubnau www.nature.com/articles/s41...