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🚨We have published our latest differentiation strategy for #stemcell derived islets. By depolymerizing F-actin at the beginning of differentiation, we enhanced β-cell formation, function, and safety for #diabetes cell therapy. 🧵below www.nature.com/articles/s41...
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This study demonstrates that cytoskeletal state at the onset of directed differentiation impacts the exit of stem cells from pluripotency and downstream lineage specification. These findings are utili...
Depolymerizing F-actin accelerates the exit from pluripotency to enhance stem cell-derived islet differentiation - Nature Communications
www.nature.com
Dr. Jeffrey Millman