🚨We have published our latest differentiation strategy for #stemcell derived islets. By depolymerizing F-actin at the beginning of differentiation, we enhanced β-cell formation, function, and safety for #diabetes cell therapy. 🧵below www.nature.com/articles/s41...
This study demonstrates that cytoskeletal state at the onset of directed differentiation impacts the exit of stem cells from pluripotency and downstream lineage specification. These findings are utili...