Hiring PhDs/Postdocs CGRLab.github.io | Assistant Professor, Data Science and AI division, Chalmers University | SciLifeLab | Formerly at JHU-Langmead, UNIL-Dessimoz, WUR
Sina Majidian
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Folddisco is now published @natbiotech.nature.com. It’s a fast motif search for similar 3D DISCOntinuous residues like catalytic sites or zinc fingers across the entire protein universe.
📄 www.nature.com/articles/s41...
💾 folddisco.foldseek.com
🌐 https://search.foldseek.com/folddisco
A big preprint from my group!
Muller Elements are considered to be conserved in flies. We tested it by reconstructing the ancestral dipteran karyotype using 340 chromosomal genomes and suprise suprise, they're not...
Led by @juliagries.bsky.social and Sam Ebdon. www.biorxiv.org/content/10.6...
🧵👇
How Can Evolution Learn?
Trends in ecology & evolution (2016)
Introducing nail - a Rust implementation of profile HMM sequence alignment for proteins. Near-HMMER sensitivity, but a lot faster:
www.biorxiv.org/content/10.1...
github.com/TravisWheele...
We’re hiring for OrthoFinder!
Great role for someone who enjoys scientific software development: Python, data analysis, workflows, Git, scalability, and making tools nicer to use.
Comparative genomics or open-source bioinformatics experience would be a lovely bonus.
my.corehr.com/pls/uoxrecru...
Benchmarking reveals the superiority of nucleic acid foundation models in predicting lncRNA coding potential
link.springer.com/article/10.1...
Genome Biology, 2026
"DNABERT-2, trained solely on DNA, performs competitively or even superior to RNA-specific models."
A novel method for across-chromosome phasing without relative data
doi.org/10.1093/bioi...
Bioinformatics, 2026
Looking to contribute to the future of #ScientificResearch 🧪 in 🇨🇭? The SNSF Research Council is recruiting 21 new members for its six committees. The mandates will start in April and October 2027. Interested?
🗓️ Apply by 14 June 2026.
www.snf.ch/en/pk2qftWyV...
Congrats to @leoackermann.bsky.social on winning RECOMB's best poster award for his work on compressing pairwise distance matrices!
Check it out here: lacker.gitlab.io/pdf/research...
Brutal and sad. The article mentions multiple scientists, but I happen to know Sean. Sean is true role model, as a scholar, engineer communicator & mentor. He has poured time into serving NIH. If the NIH / White House is kicking Sean to the curb, we're truly done for
www.npr.org/2026/05/21/n...
Even with federal grants largely restored, scientists say the Trump administration is still preventing those funds from reaching them. The consequences, they say, are already becoming clear.
Folddisco finds similar (dis)continuous 3D motifs in large protein structure databases. Its efficient index enables fast uncharacterized active site annotation, protein conformational state analysis and PPI interface comparison. 1/9🧶🧬
📄 www.biorxiv.org/content/10.1...
🌐 search.foldseek.com/folddisco
